The LNCS journal Transactions on Computational Systems Biology is
devoted to inter- and multidisciplinary research in the fields of
computer science and life sciences and supports a paradigmatic shift in
the techniques from computer and information science to cope with the
new challenges arising from the systems oriented point of view of
biological phenomena. This issue contains four highly detailed papers.
The first paper focuses on quantitative aspects of the bgl operon for
E.coli. The second contribution deals with ecosystem transitions
affecting phenotype expressions and selection mechanisms. The third
paper presents the Stochastic Calculus of Looping Sequences (SCLS)
suitable for the description of microbiological systems, such as
cellular pathways, and their evolution. The final contribution describes
the use of biological transactions to make atomic sequences of
interactions in the BlenX language.